Papers/2609.04325
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The microscope is the mask: privileged views and labels from a cryo-ET forward model

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self-supervisedprotein annotationcryogenic electron tomographysimulated data
2609.04325
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7h ago

Abstract

This paper explores the use of simulated data for training a model for protein annotation in crowded cryo-electron tomography volumes.

Reality Card

Core Claim

The CARNIVAL model outperforms a state-of-the-art model by utilizing forward model-based paired views and privileged information for protein annotation tasks.

Method / Result

CARNIVAL was evaluated without finetuning and showed improved performance on classification and detection tasks in real tomograms.

Limitations

The reliance on simulated data and specific forward model assumptions may limit generalizability to all real-world scenarios.

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